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Another reason was that, although a concentration gradient between extracellular and intracellular Acr formed, the passive diffusion of Acr across the cell membrane might heavily rely on the transport capacity of aquaglyceroporin FPS1, the loss of which confers resistance to Acr in S

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Characterization of the functional progesterone receptor in an endometrial adenocarcinoma cell line (Ishikawa): progesterone-induced expression of the alpha1 integrin